Chronic kidney disease (CKD) is one of the most important causes of pediatric morbidity, related with more mortality, and could result in
severe psychosocial damages, a negative self-image and a feeling of inferiority compared to their normal peers. Earlier age at menarche
(AAM) is related to higher risk of diabetes and then higher CKD risk. Many factors may contribute to the relationship between puberty and
CKD such as malnutrition and growth hormone. There also is a growth retardation among children with CKD which is associated with
higher morbidity and mortality.