ISSN: 2423-6438  
J Renal Endocrinol. 2016;2(1): e5.

Review

Aggravation of chronic kidney disease by inflammatory factors; a narrative review on current concepts

Masoud Amiri 1,2 *

1 Department of Epidemiology and Biostatistics, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.
2 Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
*Corresponding Author: Masoud Amiri, Ph.D, Email: m.amiri@erasmusmc.nl

Abstract

Chronic kidney disease (CKD) is a common disease worldwide with several causal factors such as inflammation, as one of the most important factors. Inflammation is in turn an outcome of many factors associated to renal dysfunctions like immune dysfunction which could act as a catalyst of many other CKD risk factors. Moreover, inflammation seems to be a logical target for preventive and remedial – general and particular anti-inflammatory interventions – in patients with CKD.

Citation: Amiri M. Aggravation of chronic kidney disease by inflammatory factors; a narrative review on current concepts. J Renal Endocrinol. 2016;2:e05.

Implication for health policy/practice/research/medical education

Systemic inflammation is a situation intrinsically associated to CKD and its other typical sequelae. In fact, inflammation is a key contributor to problems in CKD with some inflammatory markers.

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Submitted: 08 Mar 2016

Accepted: 04 May 2016
First published online: 17 May 2016
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