Introduction: Abnormal pulmonary artery pressure (PAP) in hemodialysis patients is associated with significant increase in morbidity and mortality.
Objectives: Considering the significance of pulmonary hypertension in hemodialysis patients, a study was designed to assess the association of serum adiponectin levels and PAP in a group of stable hemodialysis patients.
Patients and Methods: The study was conducted on a group of non-diabetic hemodialysis patients. The study was carried out in hemodialysis ward of Shahrekord University of Medical Sciences for a period of 4 months in 2013. The studied patients had a history of dialysis from 1 to 22 years.
Results: In our study, out of 76 hemodialysis patients, 46.1% were female and 53.9% were male. The mean PAP in female hemodialysis patients was 29.74 mm Hg, which was about 9% less than the PAP observed in male hemodialysis patients. Mean adiponectin levels in all the patients, males, and females, respectively, was 10.59, 10.42, and 10.80 μg/mL respectively. In this study a significant and positive relationship between adiponectin levels and PAP in female hemodialysis patients (r = 0.35, P = 0.04) was detected.
Conclusion: This association requires more investigation on the significant role of adiponectin in hemodialysis patients.