Sara Bahadoram
1 
, Bijan Keikhaei
1 , Mohammad Bahadoram
1,2 , Mohammad-Reza Mahmoudian-Sani
1,2 , Shakiba Hassanzadeh
3* 1 Thalassemia and Hemoglobinopathy Research Center, Research Institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
2 Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical, Sciences, Ahvaz, Iran.
3 Nickan Research Institute, Isfahan, Iran.
Abstract
The nephropathy and renal complications of sickle cell disease are associated with various events such as hypoxic or ischemic conditions and reperfusion injury. Erythrocyte sickling occurs following these events and renal medullary acidosis.