Elnaz Marzbani 1
, Rohollah Valizadeh 2
, Nasrin Tavassoli 3
, Hamid Nasri 3*
, Yassamin Rabiei 1 1
Nickan Research Institute, Isfahan, Iran.2
Urmia University of Medical Sciences, Urmia, Iran.3
Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
This is a cross-sectional investigation, which was carried out on 127 kidney biopsy proven lupus nephritis cases by lupus nephritis classification of ISN/RPS 2003. We studied demographic data of all individuals comprising serum creatinine, 24 hours proteinuria, age and gender. Our study showed no difference of serum creatinine and 24 hours proteinuria and lupus nephritis (LN) classes between age below or equal to 40 versus more than 40 years old. In this study also, we found no significant difference of antibody deposited intensity of IgG, C3 and C1q in immunofluorescence study in age below or equal to 40 versus more than 40 years old. Accordingly, no significant difference of LN classes, activity or chronicity percent between ages below or equal to 40 versus more than 40 years old. Moreover, no significant difference of number of sclerotic glomeruli or crescents among patients with ages below or equal to 40 versus more than 40 years old were detected.