Submitted: 08 Apr 2018
Accepted: 20 Jun 2018
ePublished: 08 Jul 2018
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J Ren Endocrinol. 2018;4: e19.
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Epidemiology and Prevention

Fetuin-A in kidney disease

Marziyeh Akbari 1, Hashem Nayeri 1*, Hamid Nasri 2

1 Department of Biochemistry, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
2 Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding Author: *Corresponding Author: Hashem Nayeri, Email: , Email: hnaieri@gmail.com

Implication for health policy/practice/research/medical education

Fetuin-A is a serum protein that is completely constructed by hepatic and placental cells. In hepatic and skeletal muscle cells, fetuin-A was detected to act as a natural inhibitor of insulin receptor tyrosine kinase. Recent studies detected that fetuin-A deficiency contributed to vascular calcification in chronic kidney disease and diabetes. However, exact role of fetuin-A is necessary to find in kidney health and diseases.

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