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Submitted: 04 Sep 2022
Accepted: 01 Oct 2022
ePublished: 08 Oct 2022
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J Renal Endocrinol. 2022;8: e21063.
doi: 10.34172/jre.2022.21063
  Abstract View: 84
  PDF Download: 61

Mini-Review

COVID-19 in systemic lupus erythematosus; a mini-review on current knowledge

Mahsa Rafieian 1 ORCID logo, Hamid Nasri 2* ORCID logo, Yassamin Rabiei 1 ORCID logo

1 Nickan Research Institute, Isfahan, Iran.
2 Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
*Corresponding Author: Corresponding Author: Prof. Hamid Nasri, Email: hamidnasri@yahoo.com, , Email: hamidnasri@med.mui.ac.ir

Abstract

The consequences of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection vary among persons, while some individuals are at high risk. Patients with systemic lupus erythematosus (SLE) and COVID-19 necessitate particular attention. SLE cases may be at particular risk for SARS-CoV-2 due to their dysregulated immune system and immunosuppressive treatments. Organ injury and administration of systemic glucocorticoids and other immunosuppressive agents are the risk factors for severe SARS-CoV-2. Additionally, SLE is not uncommon and could be severe in some ethnicities like African and Hispanic individuals and may be accompanied by poor outcomes of SARS-CoV-2. Thus, knowledge of the triggering immune response and therapeutic modalities in SLE and SARS-CoV-2 is necessary to guide treatment of this serious infectious disease in the background of SLE and vice versa.

Citation: Rafieian M, Nasri H, Rabiei Y. COVID-19 in systemic lupus erythematosus; a mini-review on current knowledge. J Ren Endocrinol. 2022;8:e21063. doi: 10.34172/jre.2022.21063.
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