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Review
Therapeutic effects of curcumin on kidney disease; an updated review of the current knowledge
Lillian Saberian
1 
, Niloufar Alimohammadi
2 , Farzad Koosha
3 , Hedayat Vali Rahvard
4 , Khadijeh Ahmadi
5 , Hamid Reza Jahantigh
6 , Tella Sadighpour
7* 1 Independent Researcher and Author, 151 Rosewell Avenue, Toronto, Ontario, Canada.
2 Department of Medicine, New York University, School of Medicine, New York, New York, United States.
3 Department of Oral Biology and Pathology, State University of New York at Stony Brook, New York, United States.
4 Physiotherapy Bachelor Course, Department of Physiotherapy, Babol University of Medical Science, Babol, Iran.
5 Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
6 Interdisciplinary Department of Medicine - Section of Occupational Medicine, University of Bari, Bari, Italy.
7 American University of Antigua College of Medicine, Antigua and Barbuda.
*Corresponding Author: Corresponding Author: Tella Sadighpour, Email: , Email:
tella.90s@gmail.com
Abstract
Curcumin is the essential ingredient of turmeric and one of the most potent antioxidants. It also has several biological capabilities, including anti-inflammatory, anticarcinogenic, anticoagulant, antidiabetic, antiviral, antibacterial, and antifungal effects. Therefore, curcumin has a significant potential for the treatment and control of various diseases. In kidney disorders like chronic kidney disease (CKD) and diabetic nephropathy (DN), the mechanism of kidney damage is associated with oxidative stress and inflammation. Curcumin, which has antioxidant and anti-inflammatory abilities, can alleviate kidney damage and treat kidney diseases. In patients with kidney disorders, progression to end-stage renal disease (ESRD) is critical because it increases their mortality rate. It has also been proved that curcumin could diminish such progression due to its antioxidant and anti-inflammatory potential, improving the survival rate. Besides, it has numerous nephroprotective effects that are summarized in this review.
Citation: Saberian L, Alimohammadi N, Koosha F, Rahvard HV, Ahmadi K, Jahantigh H, Sadighpour T. Therapeutic effects of curcumin on kidney disease; an updated review of the current knowledge. J Ren Endocrinol. 2022;8:e23063. doi: 10.34172/jre.2022.23063.