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Submitted: 13 Apr 2023
Accepted: 08 Jun 2023
ePublished: 14 Jul 2023
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J Ren Endocrinol. 2023;9: e25097.
doi: 10.34172/jre.2023.25097
  Abstract View: 587
  PDF Download: 417

Review

Renal effects of hydatidiform mole and choriocarcinoma

Hamid Nasri* ORCID logo

1 Nickan Research Institute, Isfahan, Iran
*Corresponding Author: Hamid Nasri, Email: hamidnasri@med.mui.ac.ir,, Email: hamidnasri@yahoo.com

Abstract

Molar pregnancy is an abnormal growth of trophoblastic tissue in the uterus. It can be either complete or partial. In complete moles, the development of the fetus is absent, while partial moles contain an abnormal gestational sac. Choriocarcinoma is a malignant form that arise from molar tissue. Hydatidiform mole and choriocarcinoma are rare and complicated diseases with numerous pathological conditions that can lead to significant kidney damage. Proteinuria, nephrotic syndrome, preeclampsia, decreased glomerular filtration rate, interstitial inflammation, crescentic glomerulonephritis, and thrombosis of the renal veins are the commonly encountered renal disorders with these diseases. Early intervention and treatment during pregnancy minimize these risks and lessen the risk of chronic kidney disease or end-stage renal failure. A multidisciplinary team approach involving obstetricians, nephrologists, pathologists, gynecologists, and radiologists is necessary for optimal management.

Citation: Nasri H. Renal effects of hydatidiform mole and choriocarcinoma. J Ren Endocrinol. 2023;9:e25097. doi: 10.34172/ jre.2023.25097.
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