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Submitted: 31 Mar 2023
Revision: 20 Jun 2023
Accepted: 26 Jun 2023
ePublished: 26 Jun 2023
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J Ren Endocrinol. 2023;9: e25120.
doi: 10.34172/jre.2023.25120
  Abstract View: 400
  PDF Download: 121

Review

Biomarkers in IgA nephropathy; an update to recent data

Rokhsare Zareie 1, Mahsa Asadollahi Hamedani 2 ORCID logo, Reyhaneh Sadeghian 2 ORCID logo, Yaser Khanchemehr 2 ORCID logo, Mahboubeh Belali Kharaji 2 ORCID logo, Elahe Zaremoghadam 3 ORCID logo, Negar Shahkarami 4 ORCID logo, Atena Samareh Fekri 5* ORCID logo

1 Department of Nursing, School of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran
2 Department of Nursing, Faculty of Nursing and Midwifery, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
3 Department of Internal Medicine, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
4 Instructor of Operating Room, School of Allied Medical Sciences, Fasa University of Medical Sciences, Fasa, Iran
5 Department of Anesthesiology, Faculty of Allied Medical Sciences, Kerman University of Medical Sciences, Kerman, Iran
*Corresponding Author: Atena Samareh Fekri, Email: atena.samarehfekri@gmail.com

Abstract

Biomarkers are molecules that can be measured in the body and can reflect disease activity or progression. They can be used to diagnose and monitor disease, predict treatment response, and identify potential therapeutic targets. Several types of biomarkers have been studied in the context of IgA nephropathy, including protein, gene expression, epigenetic, and microRNA biomarkers. Biomarkers have the potential to improve the accuracy and specificity of the diagnosis of IgA nephropathy and predict the disease progression and response to treatment. However, further studies are needed to validate their diagnostic value in larger cohorts of patients and to integrate them into clinical practice. The development of multi-omics approaches that combine different types of biomarkers may provide a more comprehensive understanding of the disease pathogenesis and potential treatments.
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