Nickan Research Institute Journal of Renal Endocrinology 2423-6438 1 1 2015 01 01 Early age at menarche and chronic kidney disease; an updated mini-review e011 e011 EN Masoud Amiri Journal Article 2018 07 04 2015 10 01 Chronic kidney disease (CKD) is one of the most important causes of pediatric morbidity, related with more mortality, and could result in severe psychosocial damages, a negative self-image and a feeling of inferiority compared to their normal peers. Earlier age at menarche (AAM) is related to higher risk of diabetes and then higher CKD risk. Many factors may contribute to the relationship between puberty and CKD such as malnutrition and growth hormone. There also is a growth retardation among children with CKD which is associated with higher morbidity and mortality.