Nickan Research Institute Journal of Renal Endocrinology 2423-6438 8 1 2022 01 01 A mini-review to the common adverse-effects of statins e25071 e25071 10.34172/jre.2022.25071 EN Hamid Nasri https://orcid.org/0000-0003-1673-5741 Journal Article 10.34172/jre.2022.25071 2022 09 25 2022 12 09 HMG-CoA (3-hydroxy-3-methyl glutaryl coenzyme A) reductase inhibitors are associated with muscle injury. Chronic kidney disease (CKD) carries a high risk for the development of statin-induced myopathy. Statin therapy decreases the absolute risk of cardiovascular diseases in patients with CKD; however, rhabdomyolysis increases with deteriorating kidney function.