Nickan Research Institute Journal of Renal Endocrinology 2423-6438 10 1 2024 01 01 The influence of maternal physical activity on gestational diabetes mellitus e25141 e25141 10.34172/jre.2024.25141 EN Afagh Hassanzadeh Rad https://orcid.org/0000-0001-6980-8866 Amirhossein Fakhre Yaseri https://orcid.org/0000-0001-8893-9802 Gelayol Chatrnour https://orcid.org/0000-0001-5074-6415 Journal Article 10.34172/jre.2024.25141 2023 11 20 2024 01 12 Gestational diabetes mellitus (GDM) is a prevalent pregnancy-related complication characterized by abnormal maternal glucose metabolism, leading to adverse pregnancy outcomes and long-term health implications. This review aims to investigate the effects of maternal physical activity during pregnancy on various aspects of GDM. It seeks to provide valuable insights into strategies for reducing the risk and severity of GDM, managing complications, and improving the overall health of both mother and fetus during pregnancy. To achieve this, we conducted a comprehensive literature search across various databases, using specific keywords related to GDM, exercise, physical activity, pregnancy, and gestational diabetes. The findings emphasize the potential of maternal physical activity as a promising strategy for preventing and managing GDM. Personalized exercise programs, supervised by qualified professionals, play a pivotal role in ensuring the safety and effectiveness of exercise during pregnancy. Adopting a holistic approach to GDM management, which includes physical activity, is crucial for enhancing the health outcomes of both the mother and the child. This review contributes to our understanding of the role of exercise in mitigating the risk and severity of GDM and its positive impact on overall maternal and fetal well-being.