Nickan Research Institute Journal of Renal Endocrinology 2423-6438 7 1 2021 01 01 Clinical profile of chronic kidney disease of unknown origin in patients of Yavatmal district, Maharashtra, India e01 e01 10.34172/jre.2021.01 EN Dhananjay Ookalkar https://orcid.org/0000-0001-8256-0594 Ashwini Ookalkar https://orcid.org/0000-0002-7807-6596 V.L. Gupta https://orcid.org/0000-0002-0681-8757 Manish R Balwani https://orcid.org/0000-0003-3923-6953 Journal Article 10.34172/jre.2021.01 2020 05 15 2020 07 17 We present a case series of patients with chronic kidney disease of unknown etiology (CKDu) coming from a well-defined geographic area, Yavatmal, district of Maharashtra, in central of India. These patients presented with advanced renal failure, variable proteinuria, and bilateral hyperechoic kidneys, largely normotensive and belonged to poor economic class from agricultural communities. The study highlights the need for large epidemiological survey in Yavatmal region to detect patients with CKDu and investigate the possible etiology.